Bioengineering implants for organ repair

In collaboration with Regenosca SA, the goal of this Innosuisse project is to develop clinical grade bioengineered implants for organ repair.

Due to the lack of adequate implants, surgeons must rely on autologous tissue patches for soft tissue repair. This is the case, inter alia, for urinary tract reconstruction, vessel replacement, and tendon/ligament repair. Harvesting of autologous tissue creates a second operation site with additional pain and complications for the patient. Tissue availability and variable tissue quality create challenges for the surgeons.

Bioengineered implants produced by Regenosca's TissueSpan technology withstand current surgical suture techniques and have shown successful regeneration of urinary tract tissue in several preclinical studies. A First-in-man study in 5 urethral stricture patients is currently ongoing with their implants. In summary, TissueSpan implants present a patient-friendly alternative to autologous tissue patches.